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STUDENT DIGITAL NEWSLETTER ALAGAPPA INSTITUTIONS

Amy C. Degnim, MD

State law prohibits the suspension pain management after shingles azulfidine 500mg for sale, expulsion pain treatment center rochester ny buy generic azulfidine 500mg line, or disciplining of a pregnant student pain treatment center houston discount azulfidine 500 mg amex. Terminating a Pregnancy Many teens lack information about what terminating a pregnancy entails a better life pain treatment center flagstaff az discount azulfidine 500 mg on-line. Immediate assessment of options and choices is imperative when an adolescent seeks help. This form contains information about: pregnancy termination procedures, possible medical problems, and choices available other than pregnancy termination. In general, an abortion may be performed only with the consent of the minor and at least one parent. If there has been a divorce, the consent of the parent with custody is sufficient. If the parents are not available, the consent of the minor and a legal guardian is sufficient. If an adolescent cannot obtain or does not want to request parental consent, she may seek authorization for an abortion from a Superior Court judge. Attorneys in Massachusetts offer their services to minors seeking judicial consent through the Committee for Public Counsel Services (617-482-6212 or. An attorney will arrange the court appointment and accompany the minor to court free of charge. Although some appropriate assistance has been developed, it is deemed to be "seriously underutilized," and development of additional materials and programs, as well as further research, is recommended. With opportunities to learn about and discuss the many dimensions of human sexuality, young people with disabilities can learn to protect themselves from such risks, develop the necessary interpersonal skills to foster healthy relationships, and learn to take responsibility for their bodies and their actions. Presenting information at an appropriate pace and with a tailored format is key, as is inclusion of information about how a specific physical disability affects expression of sexuality and participation in a sexual relationship. Gay: Preferred synonym for homosexual (grade-appropriate definitions shown below). Or a woman who falls in love with another woman (but she might prefer to call herself lesbian than gay). To some degree, gender role is clearly learned (socially constructed and culture-specific). To some degree, people are probably biologically predisposed to be more "feminine" or "masculine. Sometimes appropriate in referring to behavior (although "same-sex" is the preferred adjective). When referring to people, as opposed to behavior, "homosexual" is considered derogatory, and the terms "gay" and "lesbian" are preferred. Inter-sexed or inter-sexual: An adjective to describe a person (referred to archaically as a "hermaphrodite") who was born with an anomaly of the reproductive system - with genitals or chromosomes that were not clearly male or female. At least 1 in 2,000 children is born with genitals that make it difficult for even an expert to determine their sex. Some doctors consider anomalies such as hypospadias (in which the urethral opening is somewhere other than the tip of the penis), which occurs in 1 of every 200 baby boys, to be inter-sexed conditions. Many lesbians feel invisible when the term "gay" is used to refer to both men and women. To some degree, the qualities one finds attractive may be learned, probably in the first few years of life. In all instances, use this term instead of "sexual preference" or other misleading terminology. Sexual preference: Avoid this term; it implies a casual choice, which is rarely, if ever, the case. Transgender: An umbrella term increasingly preferred by people whose appearance, personal characteristics, or behaviors are gender role nonconforming, which includes individuals who might otherwise call themselves transsexual, cross-dressing or genderbending. It is also preferred by some people who are emotionally neither sex or both sexes or whose gender role expression is significantly different from what society expects of people of their sex or which changes from time to time. Transvestite: A person - not necessarily gay - who dresses in clothing most often associated with another gender. Additional resources for understanding the terminology and manifestations of alternative sexuality, including the hand-out "Eleven Overlapping, Complex Aspects of Sexuality," are available from the Safe Schools Coalition at. Given this, it is very important for educators and health personnel to treat these students as individuals and to understand the unique issues with which they are grappling. These include a number of index cards containing tips about how to stop anti-gay bullying or homophobic comments in a youth-centered environment and how to support transgender youth. Research indicates that targeted interventions to prevent risky behavior can be helpful. In addition, anti-bullying and anti-discrimination education for students and staff may assist in creating a climate of safety, respect, and tolerance (see Chapters 11 and 13). All youth, regardless of gender or sexual identity, should be made aware of the full range of issues, resources, and services relating to sexuality and sexual development. When appropriate, referrals to education, counseling, and support services are recommended. In 1993, the Massachusetts Board of Education voted to adopt the following steps to improve the safety of schools and school-based support services for these students: 1. Schools are encouraged to develop policies protecting gay and lesbian students from harassment, violence, and discrimination. Incidents of anti-gay abuse should be treated with the same discipline procedures as other incidents involving bias and hatred. Schools are encouraged to offer training to school personnel in violence prevention and suicide prevention. In order to prevent violence in schools, teachers, guidance counselors, and all school staff should be provided with training in violence and suicide prevention, including the particular issues/concerns of gay and lesbian students. Schools are encouraged to offer school-based support groups for gay, lesbian, and heterosexual students. In order to support students who are isolated and may be at high risk for suicide, high schools should establish support groups where all students, gay, lesbian, and heterosexual, may meet on a regular basis to discuss gay and lesbian youth issues in a safe and confidential environment. These gay/heterosexual alliances should be open to all students and should have a faculty advisor and support from the school administration. Schools are encouraged to provide school-based counseling for family members of gay and lesbian students. School systems should extend existing student support teams, guidance services, and partnerships with community agencies to provide counseling services to gay and lesbian students and their families. Just as age often determines how we communicate with children about sexuality, differences in ethnicity, language, and cultural experience can have equally vast influences on how young people think about sexual development and experience. Families who have been in this country a short time, or those who live and work in relatively insulated communities, are more likely to think about sexuality from the perspective of their country of origin. For example, Massachusetts is now home to many families emigrating from countries where young girls are expected to refrain from any sexual behavior before marriage. It is important that health educators be sensitive to both the cultural values of families and the needs of students who may be experiencing difficulty in reconciling their own values and beliefs about sexuality with those of their parents and their communities. Partnering with families and communities, schools are encouraged to implement a comprehensive and culturally-sensitive formal health curriculum for reproductive health and sexuality that is age appropriate and is accompanied by support systems for students, staff, and families. Because school attendance has been identified as a protective factor against risky sexual behavior, schools should also make every possible effort to retain and assist students, including those who are pregnant or parenting, and to create a safe atmosphere for students of all sexual orientations. It provides research briefs and tables offering essential guidance about the relative effectiveness of interventions targeting adolescent reproductive health. Produced in partnership with Child Trends, "Not Yet" provides detailed descriptions of prevention programs that have been shown through careful research to result in delayed first sex among teens. Making the List helps those working with young people to navigate lists of effective teen pregnancy prevention programs and make informed decisions about how to select the best one(s) for a particular community and population. Produced in partnership with Child Trends, No Time to Waste provides detailed descriptions of those programs for middle-school-age youth that have been shown through careful research to have a positive impact on adolescent sexual behavior. The publication provides detailed descriptions of program curriculum, costs, and evaluation results.

The report Early Warning pain and spine treatment center nj cheap azulfidine 500mg line, Timely Response: A Guide to Safe Schools pain and headache treatment center in manhasset ny quality azulfidine 500 mg, released by the U pain management shingles head discount azulfidine 500mg amex. Department of Education in 1998 pain swallowing treatment purchase 500mg azulfidine with visa, points out that "opportunities for inappropriate behaviors that precipitate violence are greater in a disorderly and undisciplined school climate. Be sure to include a description of school anti-harassment and antiviolence policies and due process rights. These values should be expressed in a statement that precedes the schoolwide disciplinary policy. Be sure rules are written and consistently applied in a nondiscriminatory manner and that they accommodate cultural diversity. Establish multiple levels of consequences, both to aid students in understanding that not all inappropriate behavior is equally serious and to provide a means of dealing with multiple violations. Strategies that have been found to support students include class discussions, student government, and participation on discipline teams. In addition, peer mediation and conflict resolution have been implemented widely in schools to promote a climate of nonviolence. Provide services and support for students who have been suspended and/or expelled. Before serious penalties such as suspension and expulsion are imposed for nonviolent acts, the impact of the disciplinary measure should be carefully considered, as well as the presence of factors such as mental illness or a difficult home situation that may have contributed to the violation (American Academy of Pediatrics, 2003). Removal from school may put professional help out of reach at a time when the student most needs it, increasing the risk that the student will use drugs or engage in other risky behaviors, drop out of school, or become suicidal. Some of these are discussed below, and others are listed in the Resources section at the end of this chapter. Guidelines Developed in 2004 with input from more than 300 health, education, and safety professionals representing more than 30 different national organizations, Health, Mental Health and Safety Guidelines for Schools assists those who play a role in the assessment, planning, or improvement of school health and safety programs. The guidelines cover the health, mental health, and safety of students and school staff while they are in school, on school grounds, on their way to or from school, or involved in school-sponsored activities. The 1999 document Protecting Students from Harassment and Hate Crime: A Guide for Schools, published by U. Measuring Violence-Related Attitudes, Behaviors, and Influences Among Youths: A Compendium of Assessment Tools (2nd ed. Many local school-based health centers in Massachusetts have incorporated effective screening tools for their staff to provide to students. Exhibit 13-4 at the end of this chapter provides a checklist of early warning signs that may indicate a child or adolescent is at greater-than-average risk of violent behavior. This tool is reprinted from A Practical Guide for Crisis Response in Our Schools, a 2003 publication of the American Academy of Experts in Traumatic Stress. Through prevention education in every grade, from kindergarten through grade 12, safety skills may be presented, practiced, and modeled. School policies need to cover a wide variety of safety issues, ranging from playground safety to prevention of sexual harassment. The school climate must be assessed at regular intervals to ensure the respectful treatment of each individual student and staff member. Through their observations and assessments of student behavioral and physical health status, school nurses are in a unique position to identify signs of child abuse, depression, harassment, and dating sexual abuse so that appropriate intervention can occur. Should injuries occur, school nurses can offer onsite assessment and first aid, providing referrals as needed. If schools are proactive in all these responsibilities, students will have opportunities to learn in a safe environment - and develop skills enabling them to incorporate lifelong habits of safety and selfcare. Lessons for preschool-age children are taught through puppet shows and reinforced by activities such as songs and skits, while primary-grade students receive information integrated into current safety and life-skills classroom instruction. Lessons can also incorporate elements of mandated math, verbal, and science curricula. It works by providing a seamless continuum of prevention, education, and treatment. This school-based curriculum links teachers with community safety experts and parents. For elementary and middle schools, the program emphasizes the use of helmets while playing sports and the use of safety belts in cars. For high schools, the program includes the consequences and costs - financial and human - of violence and drunk/drugged driving. The program helps children develop safe behavior patterns that will become lifelong habits. Traumaroo was developed in 1994 by the American Trauma Society to help reduce preventable injuries among children throughout the country. Through an additional 10-question quiz, children are given the opportunity to earn a Junior Fire Marshal certificate signed by the U. The site also offers a downloadable guide to developing and/or selecting a bicycle education program. Department of Health and Human Services; Promising Program, Safe, Disciplined and Drug-Free Schools, U. The program brings together key stakeholders in a community or neighborhood (schools, law enforcement, social services, and health agencies) under one umbrella and provides case managers available to work daily with high-risk children. Department of Education; Model Program, Office of Juvenile Justice and Delinquency Prevention, U. Department of Health and Human Services; Promising Safe and Drug-Free Schools Program, U. It aims to motivate adolescents to challenge harmful beliefs about dating abuse and take steps to form respectful relationships including learning how to effectively handle conflicts. The online materials aimed at adolescents include fact sheets, downloads, an e-newsletter, games, interactive learning tools, streaming video clips for teens to make their own movies, television and radio spots, posters, and bookmarks. The program includes research-based, teacher-friendly curricula, training for educators, and parent-education components. Department of Health and Human Services; Model Family Strengthening Program, Office of Juvenile Justice and Delinquency Prevention; Promising Program, U. Department of Education; Special Recognition Award, Office of National Drug Control Policy; YouthNet Model Program, selected for worldwide replication by the International Youth Foundation. Copies of this curriculum may be obtained from the Juvenile Justice Clearinghouse, Office of Juvenile Justice and Delinquency Prevention, P. Young children with high rates of aggressive behavioral problems have been shown to be at great risk for developing substance abuse problems, becoming involved with deviant peer groups, dropping out of school, and engaging in delinquency and violence. Department of Health and Human Services; Model Program, Office of Juvenile Justice and Delinquency Prevention; U. Its goal is to teach students how to avoid dangerous, inappropriate, or unlawful online behavior. All curriculum, outreach, and youth empowerment materials as well as the professional development program are provided at no charge to schools, school districts, and law enforcement agencies. The program makes use of: resiliency groups held at least weekly during the school day; alternative adventure activities that include ropes courses, whitewater kayaking, camping, and hiking trips; and community service in which participants are active in a number of community- and school-focused projects. Using literature and poetry, this program provides teachers with the tools to teach about this sensitive subject and is intended to be taught in either Health or English/Language Arts classes.

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To assess hospital performance for each reporting period pain treatment center memphis order 500mg azulfidine free shipping, we re-estimate the model coefficients using the data in that period pain treatment contract generic azulfidine 500mg overnight delivery. For more details pain relief treatment azulfidine 500 mg for sale, the statistical modeling approach is described fully in Appendix A and the original methodology report best pain medication for a uti azulfidine 500 mg overnight delivery. Section 4 describes the distribution of hospitals by performance category in the U. Similarly, the validation study identified one diagnosis category most often associated with unplanned readmissions that was misclassifying those readmissions as planned. These changes improve the accuracy of the algorithm by decreasing the number of readmissions the algorithm mistakenly designated as planned. Our validation study revealed that when this procedure occurs in the inpatient setting it is usually in the context of an unplanned admission. Removal of this procedure category from the potentially planned procedure list reduces the rate of misclassification of unplanned readmissions as planned. Planned admissions for chemotherapy are typically associated with a principal diagnosis of Maintenance Chemotherapy, which is always considered planned. Removal of this procedure category from the potentially planned procedure list therefore reduces the rate of misclassification of unplanned readmissions as planned. Our validation study revealed that this diagnosis category is rarely associated with planned readmissions. The addition of this diagnosis category to the acute diagnosis list reduces the misclassification of unplanned readmissions as planned. Clinically there is no situation in which a planned procedure would reasonably be performed for acute pancreatitis. Separating out the acute and non-acute diagnoses will increase the accuracy of the algorithm while still ensuring that planned cholecystectomies and other procedures can be identified. See Section 2 for a summary of the measure methodology and model riskadjustment variables. We examined trends in the frequency of patient risk factors and the model variable coefficients and compared the model performance among these datasets. We assessed logistic regression and hierarchical logistic regression model performance in terms of discriminant ability for each specialty cohort. The percentage of patients meeting each exclusion criterion in the July 2012-June 2013 dataset is presented in Figure 4. Cohort: the index admissions used to calculate the measure after inclusion and exclusion criteria have been applied. Complications: Medical conditions that likely occurred as a consequence of care rendered during hospitalization. Comorbidities: Medical conditions that the patient had in addition to his/her primary reason for admission to the hospital. Hierarchical model: A widely accepted statistical method that enables fair evaluation of relative hospital performance by accounting for patient risk factors as well as the number of patients a hospital treats. The hospital-specific effect will be negative for a better-than-average hospital, positive for a worse-than-average hospital, and close to zero for an average hospital. The hospital-specific effect is used in the numerator to calculate "predicted" readmissions. Index admission: Any admission included in the measure calculation as the initial admission for an episode of care to which the outcome is attributed. National observed readmission rate: All included hospitalizations with the outcome divided by all included hospitalizations. For this readmission measure, the outcome is readmission within 30 days of discharge. Risk-adjustment variables: Patient demographics and comorbidities used to standardize rates for differences in case mix across hospitals. Service Mix: the particular conditions and procedures of the patients with index admissions at a given hospital. Specialty Cohort: A group of index admissions for patients with related condition categories or procedure categories that are likely treated by similar care teams. Unplanned readmissions: Acute clinical events a patient experiences that require urgent rehospitalization. Prepared by Yale New Haven Health Services Corporation Center for Outcomes Research and Evaluation for the Centers for Medicare and Medicaid Services 2013;. Testing Publicly Reported 30-Day Acute Myocardial Infarction, Heart Failure, and Pneumonia Risk-Standardized Mortality and Readmission Measures in California All-Payer Data. Hierarchical Generalized Linear Models in the Analysis of Variations in Health Care Utilization. We model the probability of readmission as a function of patient age, clinically relevant comorbidities, and index condition categories with an intercept for the hospital-specific random effect. The expected number of readmissions for each cohort in each hospital is estimated using its patient mix and the average hospital-specific intercept (that is, the average intercept among all hospitals in the sample). The predicted number of readmissions for each cohort in each hospital is estimated given the same patient-mix but an estimated hospital-specific intercept. Operationally, the expected number of readmissions for each hospital is obtained by summing the expected probabilities of readmissions for all patients in the hospital. The expected probability of readmission for each patient is calculated via the hierarchical model, which applies the estimated regression coefficients to the observed patient characteristics and adds the average of the hospital-specific intercept. The predicted number of readmissions for each hospital is calculated by summing the predicted probabilities for all patients in the hospital. The predicted probability for each patient is calculated through the hierarchical model, which applies the estimated regression coefficients to the patient characteristics observed and adds the hospital-specific intercept. Specifically, for a given specialty cohort, we estimated a hierarchical logistic regression model as follows. Let Yij denote the outcome (equal to 1 if patient i is readmitted within 30 days, zero otherwise) for a patient in cohort C {1. Let M denote the total number of hospitals and mj the number of index patient stays in hospital j. The predicted number of readmissions in each cohort was calculated, using the corresponding hierarchical logistic regression model, as the sum of the predicted probability of readmission for each patient, including the hospital-specific (random) effect. The expected number of readmissions in each cohort for each hospital was similarly calculated as the sum of the predicted probability of readmission for each patient, ignoring the hospital specific (random) effect. Using the notation of the previous section, the model-specific risk-standardized readmission ratio is calculated as follows. To calculate the predicted number of admissions predCj for index admissions in cohort C=1. Bootstrapping has the advantage of avoiding unnecessary distributional assumptions. Fit the five cohort hierarchical logistic regression models using all patients within each sampled hospital. As starting values, we use the parameter estimates obtained by fitting the model to all hospitals. If some hospitals are selected more than once in a bootstrapped sample, we treat them as distinct so that we have M random effects to estimate the variance components. Thus, we draw j(b*) ~ N(j(b), var[j(b)]) for the unique set of hospitals sampled in Step 1. Ninety-five percent interval estimates (or alternative interval estimates) for the hospitalstandardized outcome can be computed by identifying the 2. This year, since the final data were obtained from a different source, we compared these data to data from our original source using a similar time period. No new variables were added to the input files; thus, our main task was to ensure that variable frequencies and distributions in the newly created input data files were consistent with data from our prior data source for similar time periods. The results are reviewed for accuracy and changes compared to data from our prior data source. Any new variable constructs and other changes in formatting to the input files are also verified.

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At 5-year follow-up iasp neuropathic pain treatment guidelines buy cheap azulfidine 500mg on-line, the bladder was preserved in 76% of patients and 65% were free of disease pain treatment center houston texas purchase azulfidine 500mg without a prescription. Patients with large and multiple tumors were more at risk of cancer recurrence than patients with single pain treatment associates west plains mo buy azulfidine 500 mg online, small tumors pain management and shingles proven azulfidine 500mg. Five patients presented a histologically atypical or malignant meningioma, twelve patients a benign one that was recurrent or rapidly progressive. In two cases radiotherapy was administered in the initial course of the disease and in 15 cases at the time of relapse. A highly conformal approach was used combining high-energy photons and protons for approximately 2/3 and 1/3 of the total dose. The authors concluded that in both benign and more aggressive meningiomas, the combination of conformal photons and protons with a dose escalated by 10-15% offers clinical improvements in most patients as well as radiological long-term stabilization. Outcomes were measured by visual acuity, tumor thickness, resolution of retinal detachment, and posttreatment complications. The authors concluded that radiotherapy is effective in treating choroidal hemangiomas with respect to visual acuity and tumor thickness but a benefit of proton therapy could not be detected. Gastrointestinal Cancers A systematic review concluded that there is insufficient evidence to recommend proton beam therapy outside of clinical trials for gastrointestinal malignancies (Allen et al. Of the 51 patients, 33 received Proton Beam Radiation Therapy: Medical Policy (Effective 09/01/2014) 9 Proprietary Information of UnitedHealthcare. Of the 51 patients, 40 (78%) showed a complete response within 4 months after completing treatment and seven (14%) showed a partial response, giving a response rate of 92% (47/51). The authors concluded that these results suggest that proton-beam therapy is an effective treatment for patients with locally advanced esophageal cancer. Further studies are required to determine the optimal total dose, fractionation schedules and best combination of proton therapy with chemotherapy. In this study, 5-year and 10-year survival rates were similar to conventional therapies as reported in the literature. The 10-year survival rate was higher for patients with low stage (89%) compared with advanced stages (40%) of cervical cancer. Head and Neck Cancers A systematic review concluded that there is insufficient evidence to recommend proton beam therapy outside of clinical trials for head and neck cancer (Allen et al. Primary outcomes of interest were overall survival, disease-free survival and locoregional control, at 5 years and at longest follow-up. A total of 43 cohorts from 41 non-comparative observational studies were included. Median follow-up for the charged particle therapy group was 38 months and for the photon therapy group was 40 months. Pooled overall survival was significantly higher at 5 years for charged particle therapy than for photon therapy and at longest follow-up. At 5 years, disease-free survival was significantly higher for charged particle therapy than for photon Proton Beam Radiation Therapy: Medical Policy (Effective 09/01/2014) 10 Proprietary Information of UnitedHealthcare. Locoregional control did not differ between treatment groups at 5 years, but it was higher for charged particle therapy than for photon therapy at longest follow-up. A subgroup analysis comparing proton beam therapy with intensity-modulated radiation therapy showed significantly higher disease-free survival at 5 years and locoregional control at longest follow-up. The authors concluded that, compared with photon therapy, charged particle therapy could be associated with better outcomes for patients with malignant diseases of the nasal cavity and paranasal sinuses. Prospective studies emphasizing collection of patient-reported and functional outcomes are strongly encouraged. A systematic review and meta-analyses were performed to retrieve evidence on tumor control, survival and late treatment toxicity. Eighty-six observational studies (74 photon, 5 carbon-ion and 7 proton) and eight comparative in-silico studies were included. Five-year local control after proton therapy was significantly higher for paranasal and sinonasal cancer compared to intensity modulated photon therapy (88% versus 66%). Although poorly reported, toxicity tended to be less frequent in carbon-ion and proton studies compared to photons. In-silico studies showed a lower dose to the organs at risk, independently of the tumor site. Except for paranasal and sinonasal cancer, survival and tumor control for proton therapy were generally similar to the best available photon radiotherapy. In agreement with included in-silico studies, limited available clinical data indicates that toxicity tends to be lower for proton compared to photon radiotherapy. Since the overall quantity and quality of data regarding proton therapy is poor, the authors recommend the construction of an international particle therapy register to facilitate definitive comparisons. Four studies included paranasal sinus cancer cases, three included nasopharyngeal cancer cases and seven included oropharyngeal, hypopharyngeal, and/or laryngeal cancer cases. All studies showed that protons had a lower normal tissue dose, while keeping similar or better target coverage. Two studies found that these lower doses theoretically translated into a significantly lower incidence of salivary dysfunction. The results indicate that protons have the potential for a significantly lower normal tissue dose, while keeping similar or better target coverage. The results of these studies should be confirmed in properly designed clinical trials. Hepatocellular Carcinoma A systematic review concluded that there is evidence for the efficacy of proton beam therapy for treating hepatocellular carcinoma but no suggestion that it is superior to photon based approaches (Allen et al. Median Proton Beam Radiation Therapy: Medical Policy (Effective 09/01/2014) 11 Proprietary Information of UnitedHealthcare. Eighteen patients subsequently underwent liver transplantation; 6 (33%) explants showed pathological complete response and 7 (39%) showed only microscopic residual. A randomized controlled trial to compare its efficacy to a standard therapy has been initiated (Bush et al. Survival at 1, 3 and 5 years for the whole cohort was 87%, 61% and 48%, respectively. A total of, 343 consecutive patients with 386 tumors, including 242 patients (with 278 tumors) who received proton therapy and 101 patients (with 108 tumors) who received carbon ion therapy, were treated on 8 different protocols of proton therapy (52. Univariate analysis identified tumor size as an independent risk factor for local recurrence in proton therapy, carbon ion therapy and in all patients. Multivariate analysis identified tumor size as the only independent risk factor for local recurrence in proton therapy and in all patients. Child-Pugh status was the only independent risk factor for overall survival in proton therapy, in carbon ion therapy, and in all patients. Randomized trials and/or comparative effectiveness research are needed to determine which patients are more likely to benefit from charged particles over photon radiation therapy. A systematic review concluded that there is insufficient evidence to recommend proton beam therapy outside of clinical trials for lung cancer (Allen et al. Proton Beam Radiation Therapy: Medical Policy (Effective 09/01/2014) 12 Proprietary Information of UnitedHealthcare. The authors found that higher doses of proton radiation could be delivered to lung tumors with a lower risk of esophagitis and pneumonitis. The most common nonhematologic grade 3 toxicities were dermatitis (n = 5), esophagitis (n = 5) and pneumonitis (n = 1). The overall survival and progression-free survival rates were 86% and 63% at 1 year. The authors concluded that concurrent high-dose proton therapy and chemotherapy are well tolerated, and the median survival time of 29. The authors assessed safety and efficacy and evaluated the main technical issues related to this treatment. However, caution is warranted due to the limited number of patients and limited length of follow-up of the particle studies. The authors searched for clinical evidence to justify implementation of particle therapy as standard treatment in lung cancer. For proton therapy, 2- to 5-year local tumor control rates varied in the range of 57%-87%. Radiation-induced Proton Beam Radiation Therapy: Medical Policy (Effective 09/01/2014) 13 Proprietary Information of UnitedHealthcare. For carbon ion therapy, the overall local tumor control rate was 77%, but it was 95% when using a hypofractionated radiation schedule.

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